The experimental researches on the use of triamcinolone acetonide for the prevention of implant capsular contracture / 中华整形外科杂志
Chinese Journal of Plastic Surgery
; (6): 368-371, 2005.
Article
in Zh
| WPRIM
| ID: wpr-240421
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To explore the use of triamcinolone acetonide for the prevention of implant capsular contracture.</p><p><b>METHODS</b>20 rabbits were randomly undivided into 2 groups of 10 animals each. Every 10 ml silicone implant was implanted beneath the panniculus carnosus muscle of one rabbit. At the same time, a modified expander catheter was mounted on the implant. This catheter has many lateral holes and the end was blind. Triamcinolone acetonide (10 mg/3 ml) was infused through the expander pot and catheter as the experimental groups. On the other hand, 3 ml saline was used as the control group at 1, 2, and 3 months. At 6 months, measures related to contracture and capsular histology examinations were performed on anesthetized animals.</p><p><b>RESULTS</b>Baker scores, capsular incision width and capsular thickness of the saline groups were evidently higher than that of triamcinolone acetonide groups (P < 0.01). Implant compression of the saline groups was evidently lower than that of triamcinolone acetonide group. Histology revealed a thinner capsules and less fibrous tissue deposition around the triamcinolone acetonide group, as compared with saline group.</p><p><b>CONCLUSIONS</b>It is effective to deliver triamcinolone acetonide to reduction of capsular contracture through the catheter and its pot.</p>
Full text:
1
Database:
WPRIM
Main subject:
Postoperative Complications
/
Triamcinolone Acetonide
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Contracture
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Breast Implantation
/
Therapeutic Uses
Limits:
Animals
Language:
Zh
Journal:
Chinese Journal of Plastic Surgery
Year:
2005
Document type:
Article