Outcomes of ICSI with sperm from different sources: a retrospective study of 431 cycles / 中华男科学杂志
National Journal of Andrology
; (12): 925-928, 2009.
Article
in Zh
| WPRIM
| ID: wpr-241229
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To compare the outcomes of intracytoplasmic sperm injection (ICSI) with retrieved epididymal and testicular sperm for obstructive azoospermia and with ejaculated sperm for severe oligozoospermia and asthenospermia.</p><p><b>METHODS</b>We retrospectively analyzed 431 ICSI cycles, which were divided according to sperm sources into Groups A (n=287 in patients with severe oligozoospermia or asthenospermia using ejaculated sperm), B (n=109 in obstructive azoospermia patients with sperm retrieved by percutaneous epididymal sperm aspiration, PESA) and C (n=35 in obstructive azoospermia patients with sperm retrieved by testicular sperm extraction, TESE). Comparisons were made among the three groups in the rates of embryo implantation, fertilization, pregnancy, cleavage, and miscarriage.</p><p><b>RESULTS</b>Group A showed statistically significant differences from Groups B and C in the rates of embryo implantation and pregnancy (18.46% vs. 25.23% and 28.76%, 31.23% vs. 42.16% and 39.39%, P < 0.05). But no significant differences were seen in the rates of fertilization, cleavage and miscarriage among the three groups (P > 0.05).</p><p><b>CONCLUSION</b>The rates of embryo implantation and clinical pregnancy are higher in patients with obstructive azoospermia than in those with severe oligozoospermia or asthenospermia after ICSI with ejaculated sperm.</p>
Full text:
1
Database:
WPRIM
Main subject:
Oligospermia
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Spermatozoa
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Testis
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Therapeutics
/
Pregnancy Outcome
/
Retrospective Studies
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Sperm Injections, Intracytoplasmic
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Cell Biology
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Epididymis
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Azoospermia
Type of study:
Observational_studies
Limits:
Female
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Humans
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Male
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Pregnancy
Language:
Zh
Journal:
National Journal of Andrology
Year:
2009
Document type:
Article