Determination of matrine, sophoridine and oxymatrine in Compound Kushen Injection by HPLC / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 222-224, 2007.
Article
in Zh
| WPRIM
| ID: wpr-246005
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To establish a high performance liquid chromatography (HPLC) method for determination of matrine, sophoridine and oxymatrine in Compound Kushen Injection.</p><p><b>METHOD</b>Alltima amino column was used with acetonitrile-3% phosphoric acid-ethyl alcohol (80:10:10) as the mobile phase and the detection wavelength was at 220 nm.</p><p><b>RESULT</b>The mean recovery of matrine, sophoridine and oxymatrine in Compound Kushen Injection was 99.51% (RSD 1. 58%), 99.24% (RSD 1.44%) and 100.22% (RSD 1.85%), respectively.</p><p><b>CONCLUSION</b>The method was simple, rapid, accurate and specific and suitable for quality control of the product.</p>
Full text:
1
Database:
WPRIM
Main subject:
Quality Control
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Quinolizines
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Drugs, Chinese Herbal
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Chemistry
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Reproducibility of Results
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Chromatography, High Pressure Liquid
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Drug Combinations
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Alkaloids
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Methods
Language:
Zh
Journal:
China Journal of Chinese Materia Medica
Year:
2007
Document type:
Article