Effects of acupuncture at "Sishencong" (EX-HN 1) on physiological functions in the sleep disorder model mouse / 中国针灸
Chinese Acupuncture & Moxibustion
; (12): 681-683, 2007.
Article
in Zh
| WPRIM
| ID: wpr-262091
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To probe into the effect of acupuncture at "Sishencong" (EX-HN 1) on sleep and the mechanism.</p><p><b>METHODS</b>Forty-eight white mice were randomly divided into a Sishencong group, a Zusanli group, a model group and a blank control group, 12 mice in each group. In the mice of the first 3 groups, sleep rhythm disorders was induced by repeatedly regular intraperitoneal injection of small dose of Caffeine, and the mice of the first two groups were treated by acupuncture at "Sishencong" (EX-HN 1) and "Zusanli" (ST 36), respectively. Living state and, circadian activities were observed, and nitric oxide synthase (NOS) activity and nitric oxide(NO) content in the brain were detected.</p><p><b>RESULTS</b>Acupuncture at "Sishencong" (EX-HN 1) or "Zusanli" (ST 36) could significantly increase NOS activity and NO content in the brain, with acupuncture at "Sishencong" (EX-HN 1) being significantly better than acupuncture at "Zusanli" (ST 36) (P < 0.01).</p><p><b>CONCLUSION</b>Acupuncture at Sishencong (EX-HN 1) treats insomnia and regulates sleep and many mental and nervous symptoms, which are carried out partially through increasing NOS activity and NO content, promoting normal function of brain tissues.</p>
Full text:
1
Database:
WPRIM
Main subject:
Psychology
/
Sleep Wake Disorders
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Therapeutics
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Brain
/
Acupuncture Points
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Acupuncture Therapy
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Nitric Oxide Synthase
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Disease Models, Animal
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Metabolism
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Nitric Oxide
Type of study:
Prognostic_studies
Limits:
Animals
Language:
Zh
Journal:
Chinese Acupuncture & Moxibustion
Year:
2007
Document type:
Article