Newborn screening in Zhejiang, China / 中华医学杂志(英文版)
Chinese Medical Journal
; (24): 702-704, 2012.
Article
in En
| WPRIM
| ID: wpr-262543
Responsible library:
WPRO
ABSTRACT
<p><b>BACKGROUND</b>It has been 11 years since newborn screening started in Zhejiang in 1999. The aim of this study was to analyze and summarize the status of newborn screening in Zhejiang from 1999 to 2009.</p><p><b>METHODS</b>Blood samples were collected from the heels of newborns 72 hours after birth. We have conducted laboratory tests that the congenital hypothyroidism (CH) and circulating levels of thyroid-stimulating hormone (TSH) was detected. Blood phenylalanine (Phe) was detected for phenylketonuria (PKU). Dissociation-enhanced lanthanide fluorescent immunoassay (DELFIA) was used for detection.</p><p><b>RESULTS</b>From 1999 to 2009, 3 875 228 newborns were screened and 2309 cases were confirmed as CH and 155 cases were confirmed as PKU. The incidence of CH and PKU were 11678 and 125 001 respectively.</p><p><b>CONCLUSION</b>In 11 years, the Zhejiang newborn screening center screened more than 3.8 million newborns, and helped more than 2000 CH and PKU patients to obtain early treatment in order to prevent physical disability and mental retardation.</p>
Full text:
1
Database:
WPRIM
Main subject:
Phenylketonurias
/
China
/
Neonatal Screening
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Congenital Hypothyroidism
/
Diagnosis
/
Methods
Type of study:
Diagnostic_studies
/
Screening_studies
Limits:
Humans
/
Newborn
Country/Region as subject:
Asia
Language:
En
Journal:
Chinese Medical Journal
Year:
2012
Document type:
Article
Publication country:
CHINA
/
CN
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REPUBLIC OF CHINA