Distribution and Antimicrobial Resistance of Streptococcus pneumoniae at Four University Hospitals in Busan and Gyeongnam / 대한임상미생물학회지
Annals of Clinical Microbiology
; : 48-53, 2016.
Article
in Ko
| WPRIM
| ID: wpr-26909
Responsible library:
WPRO
ABSTRACT
BACKGROUND: Streptococcus pneumoniae is the most common human pathogen causing community-acquired pneumonia. There is little information on the recent antimicrobial susceptibility patterns of S. pneumoniae in Busan and Gyeongnam of Korea. The aim of this study was to investigate the distribution and antimicrobial resistance of S. pneumoniae at 4 university hospitals in Busan and Gyeongnam. METHODS: We collected and analyzed the antimicrobial susceptibility results of 850 S. pneumoniae strains isolated from regional 4 university hospitals during the last 2 years from July 2013 through June 2015. RESULTS: Among 850 S. pneumoniae strains, 635 strains were isolated from respiratory specimens, followed by blood (N=121), CSF (N=13), and others (N=81). Antimicrobial susceptibility rates to penicillin, cefotaxime and ceftriaxone were 79.4%, 76.6% and 83.6%, respectively. The resistant rates to erythromycin and clindamycin were 80.9% and 68.2%, respectively. The resistant rates to levofloxacin were 9.2%. There were some differences in resistant rates by age groups, years, and specimen types. CONCLUSION: We found the changes of antimicrobial resistance of S. pneumoniae during the last 2 years. It is necessary to monitor the antimicrobial susceptibility of S. pneumoniae regularly for empirical therapy and for early detection of the changes of resistance.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Penicillins
/
Pneumonia
/
Streptococcus
/
Streptococcus pneumoniae
/
Ceftriaxone
/
Drug Resistance
/
Clindamycin
/
Cefotaxime
/
Erythromycin
/
Levofloxacin
Type of study:
Screening_studies
Limits:
Humans
Country/Region as subject:
Asia
Language:
Ko
Journal:
Annals of Clinical Microbiology
Year:
2016
Document type:
Article