Malignant fibrous histiocytoma of the retroperitoneum: an analysis of 31 cases / 中华肿瘤杂志
Chinese Journal of Oncology
; (12): 373-374, 2004.
Article
in Zh
| WPRIM
| ID: wpr-271010
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the diagnosis and treatment of malignant fibrous histiocytoma of the retroperitoneum (MFHR).</p><p><b>METHODS</b>The clinicopathological features, treatment and prognosis of 31 patients with MFHR were retrospectively analyzed.</p><p><b>RESULTS</b>The mean age of the patients was 52.7 +/- 14.1 years. MaleFemale = 229. The primary symptoms were abdominal mass and pain. The average diameter of tumor was 15 cm. The histopathologic types of the tumor were inflammatory, storiform-pleomorphic, myxoid and giant cell in 16, 10, 4 and 1 cases. The overall survival rate of 1-, 3- and 5-year was 61.3% +/- 9.8%, 31.6% +/- 11.3% and 21.1% +/- 11.4% with a median survival time of 17.0 +/- 6.3 months. Complete resection of the tumor was the major prognostic factor. Postoperative radiotherapy of 20 - 45 Gy was able to prolong the median survival from 12.1 +/- 11.6 months of surgery alone to 26.4 +/- 22.0 months of surgery plus postoperative radiotherapy though without statistical significance (P = 0.051). Postoperative CHOP chemotherapy was not shown to be beneficial.</p><p><b>CONCLUSION</b>Chemotherapy remains the important method of cure. The survival in patients with MFHR might be improved by complete resection combined with chemotherapy or/and radiotherapy.</p>
Full text:
1
Database:
WPRIM
Main subject:
Pancreatectomy
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Pathology
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Postoperative Period
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Prognosis
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Retroperitoneal Neoplasms
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Splenectomy
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General Surgery
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Therapeutics
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Vincristine
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Prednisone
Type of study:
Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limits:
Adult
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Aged
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Female
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Humans
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Male
Language:
Zh
Journal:
Chinese Journal of Oncology
Year:
2004
Document type:
Article