Levels of cytokines in peripheral blood of premature infants with chronic lung disease / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
; (12): 855-857, 2010.
Article
in Zh
| WPRIM
| ID: wpr-286965
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>This study examined the levels of interleukin (IL)-1β, IL-6, IL-8 and tumor necrosis factor alpha (TNF-α) in peripheral blood of premature infants with chronic lung disease (CLD) in order to investigate the possible role of immunologic factors in CLD.</p><p><b>METHODS</b>Twenty-six premature infants who had been admitted to the neonatal intensive care unit for 28 days were classified into CLD (n=14) and non-CLD (control, n=12) groups. IL-1β, IL-6, IL-8 and TNF-α concentrations in peripheral blood were measured by multiplex technique (Bio-plex).</p><p><b>RESULTS</b>There were no significant differences in peripheral blood levels of IL-1β, IL-6, IL-8 and TNF-α between the two groups.</p><p><b>CONCLUSIONS</b>There are no significant changes in peripheral blood levels of IL-1β, IL-6, IL-8 and TNF-α in premature infants with CLD on the non-acute phase. Immunologic factors might not play a key role in CLD on the phase.</p>
Full text:
1
Database:
WPRIM
Main subject:
Blood
/
Infant, Premature
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Chronic Disease
/
Cytokines
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Allergy and Immunology
/
Lung Diseases
Limits:
Female
/
Humans
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Male
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Newborn
Language:
Zh
Journal:
Chinese Journal of Contemporary Pediatrics
Year:
2010
Document type:
Article