Effect of fuzheng jianpi recipe on content of trace element and immune function in children with spleen deficiency anorexia / 中国中西医结合杂志

ABSTRACT

<p><b>OBJECTIVE</b>To evaluate the efficacy and prospect of Fuzheng Jianpi Recipe (FZJPR) in treating children's Spleen deficiency anorexia (CSDA) by means of observing its effect on trace element content and immune function.</p><p><b>METHODS</b>One hundred and thirty cases of CSDA were treated with FZJPR, one dose per day in decoction, orally taken, 30 days for one therapeutic course. Levels of T-lymphocyte subsets, IL-2R, immunoglobulin and trace elements were determined before and after treatment, and compared with those in the control group consisted of 60 healthy children.</p><p><b>RESULTS</b>In the treated group, abnormal figures were shown in T-lymphocyte subsets, especially in lowering of CD3 and CD4 count before treatment, and IgG content was reduced also. After treatment, CD3, CD4, CD4/CD8 ratio as well as IgG and IgA were improved significantly (P < 0.01), IL-2R percentage approached normal. Moreover, the levels of Zn and Fe changed significantly (P < 0.01).</p><p><b>CONCLUSION</b>FZJPR could improve the trace elements content and immune function in CSDA children, so it is effective in treating CSDA.</p>