Effect of propofol at different effect-site concentrations on approximate entropy of transient evoked otoacoustic emission signals in adults / 南方医科大学学报
Journal of Southern Medical University
; (12): 94-96, 2009.
Article
in Zh
| WPRIM
| ID: wpr-339056
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the effect of propofol at different effect-site concentrations on approximate entropy (ApEn) of transient evoked otoacoustic emission (TEOAE) signals in adults and investigate the possibility of using ApEn for monitoring anesthesia depth.</p><p><b>METHODS</b>Fifteen ASA class I or II patients (aged 18-49 years with normal hearing) undergoing elective surgery under general anesthesia were enrolled in this study. Anesthesia was maintained with target-controlled infusion of propofol. With the effect-site concentrations of 1, 2, 3 and 4 microg/ml, TEOAE signals were monitored and recorded before and after anesthesia. ApEn of TEOAE in 4 frequency ranges (0-2, 1-3, 2.5-4.5, and 4-6 kHz) were calculated using MATLAB software.</p><p><b>RESULTS</b>The ApEn of TEOAE in different frequency ranges showed no significant differences at the same effect-site concentration of propofol, or at different effect-site concentrations in the same frequency range (P>0.05).</p><p><b>CONCLUSION</b>Anesthesia with propofol at different effect-site concentrations does not obviously affect ApEn of TEOAE signals in adults, and ApEn can not be used as the indicator for evaluating the depth of anesthesia.</p>
Full text:
1
Database:
WPRIM
Main subject:
Pharmacology
/
Propofol
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Monitoring, Intraoperative
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Otoacoustic Emissions, Spontaneous
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Anesthetics, Intravenous
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Entropy
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Methods
Limits:
Adolescent
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Adult
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Female
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Humans
/
Male
Language:
Zh
Journal:
Journal of Southern Medical University
Year:
2009
Document type:
Article
Country of publication:
CHINA
/
CN
/
REPUBLIC OF CHINA