A follow-up of the survival and medical factors responsible for the termination of treatment in very or extremely low birth weight infants / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
; (12): 711-714, 2011.
Article
in Zh
| WPRIM
| ID: wpr-339552
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To study the outcomes of very or extremely low birth weight (VLBW/ELBW) infants born between 2000 and 2008 in a single NICU and the medical factors associated with the termination of treatment in some infants.</p><p><b>METHODS</b>In this case control study, the clinical data of 148 VLBW/ELBW infants were retrospectively studied and the surviving infants were followed up. Both univariate analysis and multivariate logistic regression analysis were used to investigate the medical factors associated with terminating treatment in infants.</p><p><b>RESULTS</b>Twenty infants (13.5%) failed to respond to the therapy and died in the hospital. Three infants (2.0%) died after discharge. Nineteen infants (12.8%) did not receive treatment due to decision of the guardian and died. Thirty infants (20.3%) were not followed up after discharge. Seventy-six infants (51.4%) survived, including 47 healthy infants, 2 cases of congenital diseases and 27 cases with poor prognosis. Multivariate logistic regression analysis showed there were 2 significant factors associated with terminating treatment: neonatal respiratory distress syndrome (P=0.030, OR=11.396, 95%CI 1.-102.701) and hospitalization periods (the year 2004-2006) (P=0.039, OR=9.869, 95%CI 1.118-87.140).</p><p><b>CONCLUSIONS</b>The survival status of VLBW and ELBW infants needs to be improved. It is important to decrease the incidence of neonatal respiratory distress syndrome for decreasing the proportion of terminating treatment in the infants.</p>
Full text:
1
Database:
WPRIM
Main subject:
Intensive Care Units, Neonatal
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Logistic Models
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Infant Mortality
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Follow-Up Studies
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Infant, Very Low Birth Weight
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Infant, Extremely Low Birth Weight
Type of study:
Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limits:
Female
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Humans
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Male
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Newborn
Language:
Zh
Journal:
Chinese Journal of Contemporary Pediatrics
Year:
2011
Document type:
Article