Preliminarily investigate the stimulating insulin secretion of Rhizoma Anemarrhenae in isolated pancreatic islets

ABSTRACT

The ethanol extract of Anemarrhena aspheloides Bunge-Liliaceae in concentration of 2, 4 and 8mg/ml increases the insulin secretion of isolated islets of normal Wistar rat and also of genetic diabetes GK incubated in glucose 3.3 or 16.7mM. So, in addition of Mangiferin, one Anemarrhena active substance having the hypoglycemic effect due to increasing the insulin sensitivity of peripheral tissues, there are the other substances directly stimulating the pancreas islets to secrete insulin