Association of HLA-Cw alleles with systemic lupus erythematosus / 中华风湿病学杂志
Chinese Journal of Rheumatology
; (12): 667-669, 2008.
Article
in Zh
| WPRIM
| ID: wpr-398309
Responsible library:
WPRO
ABSTRACT
Objective To explore the association between HLA-Cw alleles with systemic lupuserythematosus. Methods Polymerase chain reaction-sequence specific primer method was used to analyze thedistribution of HLA-Cw01-08 alleles among 108 patients with SLE and 102 healthy controls. The allelefrequencies was compared between various patient groups and the control population. Results The frequencyof HLA-Cw07 alleles in patients with SLE was significantly increased in patients with SLE. Conclusion Theresults indicate that HLA-Cw07 may be the susceptible alleles or may be closely linked to the susceptiblegenes for SLE.
Full text:
1
Database:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Rheumatology
Year:
2008
Document type:
Article