origin of cancer stem cells in hepatocellular carcinoma and its advancment / 国际肿瘤学杂志

ABSTRACT

The cancer stem cell (CSC) hypothesis presumes a small part of cells with the properties of stem cells are tu-morigenic and possess the metastatic potential and they play an important role in the genesis development and metastasis of tumor.Many studies documents show that the CSCs exit in some solid tumors,as well as in human leukemia.As one of the most common cancers,mnre and more evidences have proved that there are CSCs in hedatocellular carcinoma.