Serum 25-hydroxyvitamin D status of urban residents in Jinan / 中华老年医学杂志
Chinese Journal of Geriatrics
; (12): 429-432, 2014.
Article
in Zh
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| ID: wpr-446747
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ABSTRACT
Objective To explore the vitamin D nutritional status of urban residents in Jinan,in order to provide the basis for the prevention and treatment of chronic diseases associated with vitamin D insufficiency.Methods 1478 cases aged 30-90 years,including 602 men (59.8± 13.0) years on average and 876 women (57.4±12.9) years on average were selected by a stratified random sampling from 3 community medical care institutions in Jinan.Subjects were divided into six groups according to the 10-year interval.Serum 25-hydroxyvitamin D [25(OH) D] level was measured by enzyme-linked immunosorbent assay (ELISA).Serum [25(OH) D] level ≥ 75 nmol/L was defined as vitamin D sufficient,(50.0 ~ 74.9) nmol/L as vitamin D critical value,25.0 ~ 49.9 nmol/L as vitamin D insufficiency,< 25 nmol/L as vitamin D deficiency.All data processing and statistical analysis were finished by SPSS 13.0.Results The average level of [25 (OH) D] was 58.60 nmol/L in males [95% CI:56.7-60.5 nmol/L] and 54.17 nmol/L in females [95% CI:52.8-55.8 nmol/L],which were less than 75 nmol/L.The average level of [[25(OH) D] was 49.1nmol/L in females aged 70-79 years (95%CI:45.7~52.5 nmol/L),41.7 nmol/L in females aged 80-90 years (95%CI:38.2 ~46.7 nmol/L),which were less than 50 nmol/L.The percentage of cases with vitamin D deficiency,insufficiency,critical value,and sufficiency was 5.6%,33.4%,36.5%,24.4% in males,and 6.5%,42.9%,32.6%,18.1% in female respectively.The incidence of vitamin D deficiency and insufficiency was increased with ageing (male:x2 =33.68 P<0.01,female:x2 =55.7,P<0.001).The percentage of vitamin D deficiency and insufficiency was more in females than in males (60-69 years old:x2=9.387,P<0.05,80-90 years old:x2=8.896,P<0.05).The [25 (OH) D] level was lowest in winter (48.8 nmol/L,95%CI:46.8~50.9 nmol/L) and highest in autumn (60.2 nmol/L,95% CI:58.0~62.3 nmol/L).The incidence of vitamin D deficiency and insufficiency was highest in winter (x2 =18.364,P<0.05).Conclusions Vitamin D deficiency and insufficiency are widely prevalent in urban residents,which is more severe in the elderly and females.Serum [25(OH) D] level is related to season,and the vitamin D deficiency and insufficiency are severe in winter.
Full text:
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Database:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Geriatrics
Year:
2014
Document type:
Article