The investigation of urine iodine and blood TSH levels in 695 neonates and urine iodine level in their mothers in ;Yunnan province / 临床儿科杂志

ABSTRACT

Objective To explore the levels of urine iodine in mothers and urine iodine and blood thyroid-stimulating hormone (TSH) in their neonates, and the correlations. Methods A total of 695 pairs of mothers and their neonates were included. Urine sample of both mothers and newborns were collected and the levels of urine iodine were detected. Heel blood sample of newborns were collected and the levels of TSH were detected. Results The median urine iodine level in 695 mothers was 212 . 9μg/L, among whom 163 case ( 34 . 39%) were iodine deifcient (?5 mIU/L in neonates whose mother were iodine deifcient or excessive were higher than those in neonates whose mother were iodine adequate or more than adequate, and the difference was statistically signiifcant (Piodine in mothers was adequate, but there was still a high proportion of iodine deifciency or excess. The levels of urinary iodine in mothers were closely related to those in newborns. There is a high risk for mothers with iodine deifciency or excess to give birth to infants with higher level of TSH.