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Determination of Two Constituents in Compound Streptomycin Cream / 中国药房
China Pharmacy ; (12)2001.
Article in Zh | WPRIM | ID: wpr-525109
Responsible library: WPRO
ABSTRACT

OBJECTIVE:

To determine streptomycin sulfate and sulfonamide in compound streptomycin cream by UV spectrophotometry.

METHODS:

The maltol-ammonium ferric sulfate colourimetry was adopted in which the ammonium ferric sulfate was taken as the developer,the absorbability of streptomycin sulfate was determined with the wavelength at521nm;The absorbability of sulfonamide was determined at a wavelength of251nm with0.1%mol/L NaOH taken as the sol-vent.

RESULTS:

The linear ranges of streptomycin sulfate and sulfonamide were200~950?g/ml(r=0.9994)and1.464~7.784?g/ml(r=0.9998)respectively;Their respective average recovery were99.1%(RSD=1.90%)and99.7%(RSD=1.60%).

CONCLUSION:

The method can be used as the quality control for compound streptomycin cream.
Key words
Full text: 1 Database: WPRIM Language: Zh Journal: China Pharmacy Year: 2001 Document type: Article
Full text: 1 Database: WPRIM Language: Zh Journal: China Pharmacy Year: 2001 Document type: Article