Determination of Two Constituents in Compound Streptomycin Cream / 中国药房
China Pharmacy
; (12)2001.
Article
in Zh
| WPRIM
| ID: wpr-525109
Responsible library:
WPRO
ABSTRACT
OBJECTIVE:
To determine streptomycin sulfate and sulfonamide in compound streptomycin cream by UV spectrophotometry.METHODS:
The maltol-ammonium ferric sulfate colourimetry was adopted in which the ammonium ferric sulfate was taken as the developer,the absorbability of streptomycin sulfate was determined with the wavelength at521nm;The absorbability of sulfonamide was determined at a wavelength of251nm with0.1%mol/L NaOH taken as the sol-vent.RESULTS:
The linear ranges of streptomycin sulfate and sulfonamide were200~950?g/ml(r=0.9994)and1.464~7.784?g/ml(r=0.9998)respectively;Their respective average recovery were99.1%(RSD=1.90%)and99.7%(RSD=1.60%).CONCLUSION:
The method can be used as the quality control for compound streptomycin cream.
Full text:
1
Database:
WPRIM
Language:
Zh
Journal:
China Pharmacy
Year:
2001
Document type:
Article