Effects of polycylic aromatic hydrocarbons on plasma monoamine neurotransmitters / 重庆医科大学学报
Journal of Chongqing Medical University
; (12)2003.
Article
in Zh
| WPRIM
| ID: wpr-581145
Responsible library:
WPRO
ABSTRACT
Objective:
To explore the effect of polycylic aromatic hydrocarbons (PAHs)on plasma monoamine neurotransmitters.Methods:
80 healthy adult male coke oven workers were selected from a coke plant of a state-owned steel enterprise,80 controls were selected from the oxygen factory. Concentration of benzo[a]pyrene(B[a])P in the working environment was monitored by high performance liquid chromatography(HPLC)with fluorescence detector. The level of urinary 1-hydroxypyrene(1-OHP)was determ ined by HPLC with fluorescence detector.The plasma noradrenaline(NE),adrenaline(AD),dopamine(DA)and serotonin(5-HT)levels were measured by high performance liquid chromatography (HPLC) with electrochemical detection.Results:
In the working environment of B[a]P, concentration in coke oven workers were significantly higher than controls (P
Full text:
1
Database:
WPRIM
Language:
Zh
Journal:
Journal of Chongqing Medical University
Year:
2003
Document type:
Article