The relationship between oxidative stress and endothelium-dependent vasodilatation in obese subjects / 中国糖尿病杂志
Chinese Journal of Diabetes
; (12)1994.
Article
in Zh
| WPRIM
| ID: wpr-590947
Responsible library:
WPRO
ABSTRACT
Objective To evaluate the relationship of the levels of serum oxide and antioxide with endothelium-dependent vasodilatation(EDV) in obese subjects and to explore the effect of oxidative stress on endothelial dysfunction in obese subjects. Methods 20 euglycemic obese males (Ob) and 13 age- matched normal controls (NC) underwent euglycemic hyperinsulinemia clamp study to evaluate the peripheral glucose disposal rate (GDR) in steady-state and brachial artery ultrasound studies to assess the endothelium-dependent vasodilatation (EDV). The serum levels of ROS, MDA, GSH-PX, GSH and free fatty acids (FFAs) were measured. Results The serum ROS, MDA and FFA concentrations were significantly higher in Ob group than in the controls (P
Full text:
1
Database:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Diabetes
Year:
1994
Document type:
Article