Study of using mitomycine in the prevention of adhesion formation affter endoscopic sinus surgery

ABSTRACT

A prospective study was carried out on 32 patients in order to assess effect of mitomycine C in the prevention of adhesion formation after endoscopic sinus surgery on high-risk patients. The risk factors of post-operative adhesion included narrow nasal passages (9%), recurrent sinusitis with obstructive scar (22%). 88% mucous membrane was normal 6 months after surgery, 6% was mild adhesion after surgery. Results: administration of mitomycine C 0,04mg on the surface of sinus mucous membrane within 4 minutes, it showed high effectiveness of post-operative anti-adhesion in high-risk patients. There wasn’t any complication