Reagent-free determination of amikacin content in amikacin sulfate injections by FTIR derivative spectroscopy in a continuous flow system / 药物分析学报
Journal of Pharmaceutical Analysis
; (6): 125-131, 2014.
Article
in Zh
| WPRIM
| ID: wpr-672133
Responsible library:
WPRO
ABSTRACT
The quantitative estimation of amikacin (AMK) in AMK sulfate injection samples is reported using FTIR-derivative spectrometric method in a continuous flow system. Fourier transform of mid-IR spectra were recorded without any sample pretreatment. A good linear calibration (r40.999, %RSDo 2.0) in the range of 7.7-77.0 mg/mL was found. The results showed a good correlation with the manufacturer's and overall they all fell within acceptable limits of most pharmacopoeial monographs on AMK sulfate.
Full text:
1
Database:
WPRIM
Language:
Zh
Journal:
Journal of Pharmaceutical Analysis
Year:
2014
Document type:
Article