Expression of PTN gene in glioma, hepatoma and laryngeal squamous cell carcinoma / 第二军医大学学报
Article
in Zh
| WPRIM
| ID: wpr-677445
Responsible library:
WPRO
ABSTRACT
Objective:To investigate the role of pleiotrophin (PTN) gene in carcino genesis using cDNA microarray and in situ hybridization. Methods:The expression of PTN gene in 5 cases of glioma, 10 laryngeal squamous cell carcinoma, 6 cases of hepatocarcinoma, and normal controls were detected by BioDoor 4096 type cDNA microarray and in situ hybridization. Results: The expression of PTN gene in carcinoma samples were significantly higher than in normal controls by cDNA microarray, the results was the same as by in situ hybridization. Conclusion: cDNA microarray is an effective technique in analysis of functional study of associated genes in carcinoma. High expression of PTN gene might be correlated with mechanism of multiple carcinoma. [
Full text:
1
Database:
WPRIM
Language:
Zh
Journal:
Academic Journal of Second Military Medical University
Year:
2000
Document type:
Article