Research progress on plastic bronchitis / 中华实用儿科临床杂志

ABSTRACT

Plastic bronchitis is a rare,multisystem,clinical syndrome characterized by endobronchial,tubular,and localized or extensive obstruction resulting in acute fatal respiratory distress.The disease is more common in infectious diseases in China,but it is reported abroad after the operation of congenital heart disease.The treatment of plastic bronchitis is a challenging problem with a high mortality rate and no effective treatment has been introduced.The bronchoscope as an acute phase can only relieve symptoms of treatment recognized by domestic and foreign scholars,drug treatment is various,but there is no uniform standard,bronchodilators,hypertonic saline,leukotriene modifiers,macrolides,glucocorticoid,mucolytic agent,heparin,fibrinolytic agents,heart replacement and cardiopulmonary replacement therapy has been mentioned in clinical application.The pathogenesis of plastic bronchitis is not clear and the clinical manifestations are diverse.Early diagnosis and treatment are particularly important.