Radiocontrast media-induced acute generalized exanthematous pustulosis: A safe administration of alternative radiocontrast media using patch tests
Allergy, Asthma & Respiratory Disease
; : 270-273, 2018.
Article
in Ko
| WPRIM
| ID: wpr-716875
Responsible library:
WPRO
ABSTRACT
Acute generalized exanthematous pustulosis (AGEP) is rarely caused by radiocontrast media (RCM). The role of skin tests for the diagnosis and evaluation of cross-reactivity in a delayed type of RCM-induced hypersensitivity have yet to be determined. Here, we report a case of iodixanol-induced AGEP where we safely administered alternative RCM using patch tests. A 44-year-old woman had coronary artery angiography (CAG) for the evaluation of ischemic heart disease. She was on regular hemodialysis because of end-stage renal disease. She was given iodixanol (Visipaque) during CAG. Approximately 1 day after CAG, she developed AGEP. The patient was rehospitalized for CAG again after 1 year. We performed skin tests to choose safe alternative RCM. Intradermal tests with iodixanol, iohexol (Bonorex) and Iopamidol (Pamiray) showed negative responses. Patch tests showed a positive response to iodixanol, equivocal to iohexol, and negative to Iopamidol. We finally chose Iopamidol and performed CAG successfully without any adverse reaction. Patch tests may be a useful tool for the diagnosis and choice of safe alternatives in RCM-induced delayed-type hypersensitivity reactions such as AGEP.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Iohexol
/
Iopamidol
/
Intradermal Tests
/
Patch Tests
/
Skin Tests
/
Angiography
/
Renal Dialysis
/
Myocardial Ischemia
/
Contrast Media
/
Coronary Vessels
Type of study:
Diagnostic_studies
Limits:
Adult
/
Female
/
Humans
Language:
Ko
Journal:
Allergy, Asthma & Respiratory Disease
Year:
2018
Document type:
Article