Conventional papillary thyroid carcinoma: effects of cystic changes visible on ultrasonography on disease prognosis
Ultrasonography
; : 291-297, 2014.
Article
in En
| WPRIM
| ID: wpr-731123
Responsible library:
WPRO
ABSTRACT
PURPOSE: To investigate the characteristics of papillary thyroid carcinoma (PTC) with cystic changes visible on ultrasonography (US). METHODS: This study included 553 PTCs in 553 patients between January 2003 and August 2004. One radiologist with 10 years of experience in thyroid imaging retrospectively reviewed the preoperative US images. Two different groups were formed according to two different reference points (group 1, 25%; group 2, 50%) of the cystic component. Patients between the groups were compared according to their clinicopathologic characteristics. Disease-free survival (DFS) was estimated. Cox's multivariate proportional hazards regression model was used to identify the effect of variable factors on the recurrence risk. RESULTS: Fifty-six patients (10.1%) were confirmed to have tumor recurrence within the follow-up period. Thirty-five patients had regional metastasis, one had distant metastasis, eight had multiple site metastases, and 12 had biochemical recurrence. PTC patients with a 50% (hazard ratio [HR], 1.118; 95% confidence interval [CI], 0.255 to 4.910; P=0.883) or those with a >25% cystic component (HR, 0.569; 95% CI, 0.164 to 1.976; P=0.375), respectively. Moreover, independent predictors of recurrence were pathologic size, male gender, and lymph node metastasis, not a >50% or >25% cystic component. CONCLUSION: The proportion of the cystic component in PTCs did not affect DFS.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Prognosis
/
Recurrence
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Thyroid Gland
/
Thyroid Neoplasms
/
Retrospective Studies
/
Follow-Up Studies
/
Ultrasonography
/
Thyroid Nodule
/
Disease-Free Survival
/
Lymph Nodes
Type of study:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Humans
/
Male
Language:
En
Journal:
Ultrasonography
Year:
2014
Document type:
Article