A new naphthaldehyde derivative from Comastoma pulmonarium and its anti-tobacco mosaic virus (anti-TMV) activity / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 3884-3886, 2018.
Article
in Zh
| WPRIM
| ID: wpr-775402
Responsible library:
WPRO
ABSTRACT
A new naphthaldehyde derivative has been isolated from Comastoma pulmonarium by using various chromatographic techniques, including silica gel, Sephadex LH-20, MCI-gel resin and RP-HPLC. This compounds was determined as 5-methoxy-2-methyl-7-(2-oxopropyl)naphthalene-1-carbaldehyde(1) by NMR, MS, IR and UV spectra. This compound was also evaluated for its anti-tobacco mosaic virus (anti-TMV) activity. The result showed that it showed high anti-TMV activity with inhibition rate of 32.8%. The inhibition rate is close to that of positive control (ningnanmycin).
Key words
Full text:
1
Database:
WPRIM
Main subject:
Antiviral Agents
/
Pharmacology
/
Nicotiana
/
Tobacco Mosaic Virus
/
Chemistry
/
Chromatography, High Pressure Liquid
/
Gentianaceae
/
Aldehydes
/
Phytochemicals
/
Naphthalenes
Language:
Zh
Journal:
China Journal of Chinese Materia Medica
Year:
2018
Document type:
Article