Four new corynanthe-type alkaloids from the roots of Alstonia scholaris / 中国天然药物
Chinese Journal of Natural Medicines (English Ed.)
; (6): 918-923, 2019.
Article
in En
| WPRIM
| ID: wpr-781237
Responsible library:
WPRO
ABSTRACT
Four new corynanthe-type alkaloids, meloslines C-F (1-4), together with four known ones (5-8) were isolated from the roots of Alstonia scholaris. Their structures including absolute configurations were elucidated by extensive spectroscopic analysis and electronic circular dichroism (ECD) calculation. Compounds 1 and 2 exhibited potent vasorelaxant activity on endothelium-intact renal arteries precontracted with KCl.
Full text:
1
Database:
WPRIM
Language:
En
Journal:
Chinese Journal of Natural Medicines (English Ed.)
Year:
2019
Document type:
Article