Effect of minimally invasive anterior lateral approach for total hip arthroplasty on serum type I collagen propeptide, tartrate-resistant acid phosphatase 5b and hip joint function in patients with femoral neck fracture / 中国骨伤
China Journal of Orthopaedics and Traumatology
; (12): 1117-1122, 2019.
Article
in Zh
| WPRIM
| ID: wpr-781680
Responsible library:
WPRO
ABSTRACT
OBJECTIVE@#To analyze the level of serum N-terminal propeptide of type I precollagen (PINP) and tartrate resistant acid phosphatase 5b(TRACP-5b) in patients with femoral neck fracture(FNF) after minimally invasive anterior lateral approach with total hip arthroplasty and the effects of hip function.@*METHODS@#From September 2016 to May 2017, 98 cases of femoral neck fracture were divided into control group and observation group, 49 cases in each group. There were 49 patients in control group, including 30 males and 19 females, ranging in age from 63 to 72 years old, who underwent minimally invasive anterolateral total hip arthroplasty. There were 49 patients in observation group, including 29 males and 20 females, ranging in age from 62 to 73 years old, who underwent minimally invasive anterolateral total hip arthroplasty. The perioperative conditions(operation time, bleeding volume, incision length, hospitalization time), bone metabolism indexes including PINP, TRACP-5b, fibroblast growth factor(FGF), bone gla-protein(BGP), propetide carboxy-terminal procollagen (PICP), bone-specific alkaline phosphatase(BAP), and pain mediators such as prostaglandin E2 (PGE2) and 5-hydroxytrytamine (5-HT) levels were compared between the two groups. The hip joint function and complications were evaluated.@*RESULTS@#The operation time of the observation group was longer than that of the control group(0.05). PINP, fibroblast growth factor, BGP, PICP and BAP in observation group were higher than those in control group 1 month after operation, and TRACP-5b was lower than those in control group(0.05).@*CONCLUSIONS@#Minimally invasive anterolateral approach total hip arthroplasty is safe and reliable, and can improve hip function, improve bone metabolism, promote fracture healing, alleviate pain in patients with femoral neck fracture, which is worthy of promotion.
Key words
Full text:
1
Database:
WPRIM
Main subject:
General Surgery
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Treatment Outcome
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Minimally Invasive Surgical Procedures
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Arthroplasty, Replacement, Hip
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Collagen Type I
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Femoral Neck Fractures
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Tartrate-Resistant Acid Phosphatase
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Hip Joint
Limits:
Aged
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Female
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Humans
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Male
Language:
Zh
Journal:
China Journal of Orthopaedics and Traumatology
Year:
2019
Document type:
Article