Botulinum Toxin Injection for the Treatment of Delayed Gastric Emptying Following Pylorus-Preserving Gastrectomy: an Initial Experience
Journal of Gastric Cancer
; : 173-179, 2017.
Article
in En
| WPRIM
| ID: wpr-80095
Responsible library:
WPRO
ABSTRACT
PURPOSE:
To report our experience of endoscopic botulinum toxin injection in patients who experienced severe delayed gastric emptying after pylorus-preserving gastrectomy (PPG). MATERIALS ANDMETHODS:
We reviewed the medical records of 6 patients who received the botulinum toxin injection. They presented with severe delayed gastric emptying in the early postoperative period. Endoscopic botulinum toxin was administered as 4 injections of 25−50 IU into each of the 4 quadrants of the prepyloric area.RESULTS:
All botulinum toxin injections were successful without any complications, enabling 5 patients to tolerate soft solid diets and one to tolerate a soft fluid diet within 10 days. The endoscopic criteria of 4 patients improved. Symptom recurrence caused 2 patients to undergo repeat injections that were successful. The median follow-up period was 27 months, and all patients could ingest normal regular diets at the last follow-up.CONCLUSIONS:
Endoscopic botulinum toxin injection is a feasible treatment option for early delayed gastric emptying after PPG.Key words
Full text:
1
Database:
WPRIM
Main subject:
Postoperative Period
/
Recurrence
/
Botulinum Toxins
/
Medical Records
/
Follow-Up Studies
/
Gastroparesis
/
Diet
/
Endoscopy
/
Gastrectomy
/
Gastric Emptying
Type of study:
Observational_studies
/
Prognostic_studies
Limits:
Humans
Language:
En
Journal:
Journal of Gastric Cancer
Year:
2017
Document type:
Article