Study on Optimization of the Extraction Technology of Total Vitamin E in Euryale ferox by Box-Behnken Design-response Surface Methodology / 中国药房
China Pharmacy
; (12): 1497-1501, 2019.
Article
in Zh
| WPRIM
| ID: wpr-816913
Responsible library:
WPRO
ABSTRACT
OBJECTIVE: To optimize the extraction technology of total vitamin E in Euryale ferox. METHODS: With the extraction amount of total vitamin E as reference index, using extraction time, extraction times, ultrasound power and comminution degree as reference factors, single fator test and Box-Behnken design-response surface methodology was used to optimize the extraction technology of total vitamin E from E. ferox. The validation tests were conducted for 3 times (the amounts of E. ferox were 2.0, 20.0, 40.0 g). RESULTS: The optimal extraction technology of vitamin E included that extraction time of 80 min, extraction times of 3 times, ultrasound power of 240 W, comminution degree of 80 mesh. In validation test, extraction rates of total vitamin E were 2.063, 2.103, 2.085 mg/g (RSD=2.6%, 1.5%, 1.3%, n=3), the relative errors of which to predicted value (2.092 mg/g) were 0.14%, 0.53% and 0.33%, respectively. CONCLUSIONS: The optimal extraction technology is reasonable, stable and feasible, and can be used for the extraction of total vitamin E in E. ferox.
Full text:
1
Database:
WPRIM
Type of study:
Prognostic_studies
Language:
Zh
Journal:
China Pharmacy
Year:
2019
Document type:
Article