Genetic diagnosis in chronic diarrhea in children / 中国实用儿科杂志

ABSTRACT

Chronic diarrhea in children is a common digestive system disease with many types,and the clinical symptoms are complex. The symptoms of various chronic diarrhea diseases often overlap,so it is difficult to diagnose. Gene detection is an effective method for making diagnosis. In recent years,the progress of molecular diagnosis technology,especially the wide application of second generation gene sequencing(NGS)technology,has reduced the cost and time of gene detection. Therefore,selecting the appropriate gene diagnosis strategies and interpreting the reports are very important for clinicians.