Preparation and formulation optimization of wound dressings with nitrocellu-lose as membrane material / 药学实践杂志
Journal of Pharmaceutical Practice
; (6): 301-306, 2020.
Article
in Zh
| WPRIM
| ID: wpr-823094
Responsible library:
WPRO
ABSTRACT
Objective To prepare a wound dressing using nitrocellulose as a membrane and optimize its formulation. Methods Partial analysis was performed on commercial available products. The wound dressings were prepared by using nitrocellulose as a film-forming material, benzyl alcohol as a bacteriostatic agent, castor oil as a plasticizer, isopropyl palmitate as a skin emollient, camphor as a fragrance, and isopropyl alcohol, ethyl acetate and butyl acetate as volatile solvent. The tensile strength, breakpoint elongation percentage, breathability and waterproof performance were tested and evaluated. Results The film-forming performance of the prepared liquid wound dressing was good. The final use amount of nitrocellulose was determined to be 6%. The use amount of plasticizer castor oil was determined to be 4%. Conclusion The prepared liquid wound dressing has good film-forming property, good mechanical property, good waterproof and certain breathability.
Full text:
1
Database:
WPRIM
Language:
Zh
Journal:
Journal of Pharmaceutical Practice
Year:
2020
Document type:
Article