Application of Organoids in Lung Cancer Precision Medicine / 中国肺癌杂志
Chinese Journal of Lung Cancer
; (12): 615-620, 2020.
Article
in Zh
| WPRIM
| ID: wpr-826933
Responsible library:
WPRO
ABSTRACT
Precision medicine is an approach to rational treatment selection in the overall management of lung cancer nowadays. The introduction of the patient-derived organoid (PDO) model has established the "black-box" decision-making system from the perspective of in-vitro functional models. This may assist as a complement to the treatment selection strategy based on gene-drug correlation. Further validation must be done in multi-dimensional characteristics recapitulation of the primary tumor in organoids and in large-scale randomized controlled clinical trials. This article will give an introduction to the organoid model and review the application scenarios of organoids in the context of the precise treatment of existing lung cancer.
Full text:
1
Database:
WPRIM
Type of study:
Clinical_trials
/
Prognostic_studies
Language:
Zh
Journal:
Chinese Journal of Lung Cancer
Year:
2020
Document type:
Article