A new lignan glucoside from root of Paeonia lactiflora / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 2903-2906, 2020.
Article
in Zh
| WPRIM
| ID: wpr-828069
Responsible library:
WPRO
ABSTRACT
A new lignan glucoside,(+)-fragransin A_2-4-O-β-D-glucopyranoside(1), has been isolated from the dry root of Paeonia lactiflora by column chromatography on silica gel, Sephadex LH-20, and MCI-gel resin, as well as preparative RP-HPLC. The structure of the new compound was elucidated by spectroscopic data analysis(MS, UV, IR, CD, 1 D and 2 D NMR) and chemical method. Compound 1 showed moderate inhibition against lipopolysaccharide induced nitric oxide production in RAW264.7 macrophages, with an IC_(50) value of 21.3 μmol·L~(-1).
Key words
Full text:
1
Database:
WPRIM
Main subject:
Plant Extracts
/
Chromatography, High Pressure Liquid
/
Lignans
/
Paeonia
/
Glucosides
Language:
Zh
Journal:
China Journal of Chinese Materia Medica
Year:
2020
Document type:
Article