Correlation of estrogen receptor-alpha 36 and cancer / 肿瘤

ABSTRACT

Estrogen receptor-alpha 36 (ER-α36), which is a new type of ER with a relative molecular weight of 3.57×104, has been demonstrated to have many important physiological functions in different tissues and organs in recent years. Many studies have shown that the occurrence and development of cancer are closely related to the expression level of ER-α36, which suggests that ER-α36 may serve as a potential therapeutic target in the treatment of some cancers. This paper reviews the advances in research on the correlation between ER-α36 and some cancers such as breast cancer, gastric cancer, liver cancer, and so on.