CT manifestations of bladder neuroendocrine tumors with different pathological grades / 中国医学影像技术

ABSTRACT

Objective: To observe CT manifestations of bladder neuroendocrine tumors (NET) with different pathological grades. Methods: Clinical, pathological and CT data of 17 patients with bladder NET confirmed with pathology were retrospectively analyzed. According to the WHO 2010 pathological classification standard, all tumors were classified and then divided into low-grade group (G1 and G2) and high-grade group (G3). The differences of clinical and CT findings were compared between 2 groups. Results: Among 17 cases of bladder NET, 6 were G1, 2 were G2 and 9 were G3 tumors. There were 8 cases in low-grade group and 9 cases in high-grade group, respectively. Statistically differences of patients gender and ages (t=-3.43) (P=0.03, 0.04), also of the maximum tumor size, cystic change or necrosis, peripheral invasion and metastasis were found between 2 groups (all P<0.05). The arterial absolute enhancement degree of tumors in low-grade group ([58.62±12.45]HU) was higher than that in high-grade group ([31.88±8.86] HU) (t=5.15, P<0.01). Conclusion: CT manifestations of bladder NET with different pathological grades had certain characteristics, being helpful to diagnosis combined with clinical data.