The evaluation value of heparin-binding protein in pulmonary infection and severity of pulmonary infection / 中国小儿急救医学

ABSTRACT

Severe pulmonary infection is one of important causes of death for children under five years old in China, and early identification of the cause and severity of lung infections is important for guiding clinical interventions. Heparin-binding protein (HBP) is a protein with bactericidal activity, and its concentration is very low in healthy people. Lung bacterial infection, acute lung injury or acute respiratory distress syndrome, which can lead to permeability of vascular endothelial cells increased, thus HBP in blood or tissue fluid can be significantly increased. It has certain guiding significance for the early identification of bacterial infection and judgment of the severity of the disease. This study reviewed the evaluation role of HBP in lung infection and severity of illness.