Progress study of the relationship between diabetes mellitus and hepatocellular carcinoma / 中华肝胆外科杂志

ABSTRACT

Both diabetes and hepatocellular carcinoma are important global health issues. A large number of studies have confirmed that diabetes and hepatocellular carcinoma are inseparable. The main reasons include the imbalance of insulin-like growth factor system caused by insulin resistance, increased reactive oxygen species and disorder of adipokines. Hepatitis C virus infection may also cause diabetes. This article reviewed the common pathogenesis and related pathways of the two diseases, and provided therapeutic options for the diseases.