Penicillamine-induced virginal mammary hypertrophy
Archives of Aesthetic Plastic Surgery
; : 35-38, 2021.
Article
in En
| WPRIM
| ID: wpr-874227
Responsible library:
WPRO
ABSTRACT
Virginal mammary hypertrophy (VMH), also known as juvenile mammary hypertrophy, is characterized by excessive enlargement of the breasts. Especially in adolescent patients, this condition can cause a negative body image to develop and result in significant psychological stress. Furthermore, social problems can arise from difficulties in finding appropriately-fitting attire and having trouble exercising. Although the mechanism of VMH has not been fully elucidated, several associated drugs have been identified. In this report, we present a 15-year-old female patient with Wilson disease who developed macromastia after administration of penicillamine for 8 months. Despite cessation of penicillamine for 3 months, the condition remained stable; thus, reduction mammoplasty was performed. After surgery, the patient was able to return to activities of daily living. Although rare, physicians should be aware of the fact that penicillamine can cause VHM. Therefore, patients with Wilson disease should be checked regularly for changes in breast volume in order to minimize possible complications.
Full text:
1
Database:
WPRIM
Type of study:
Prognostic_studies
Language:
En
Journal:
Archives of Aesthetic Plastic Surgery
Year:
2021
Document type:
Article