Effect of / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences
; (12): 356-363, 2021.
Article
in En
| WPRIM
| ID: wpr-878371
Responsible library:
WPRO
ABSTRACT
Objective@#This study aimed to investigate the effects of @*Methods@#In this study, 0.1% DMG was supplemented in 20% casein diets that were either folate-sufficient (20C) or folate-deficient (20CFD). Blood and liver of rats were subjected to assays of Hcy and its metabolites. Hcy and its related metabolite concentrations were determined using a liquid chromatographic system.@*Results@#Folate deprivation significantly increased pHcy concentration in rats fed 20C diet (from 14.19 ± 0.39 μmol/L to 28.49 ± 0.50 μmol/L; @*Conclusion@#DMG supplementation exhibited hypohomocysteinemic effects under folate-sufficient conditions. By contrast, the combination of folate deficiency and DMG supplementation has deleterious effect on pHcy concentration.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Sarcosine
/
Biomarkers
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Random Allocation
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Chromatography, Liquid
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Rats, Wistar
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Dietary Supplements
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Diet
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Folic Acid Deficiency
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Homocysteine
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Liver
Limits:
Animals
Language:
En
Journal:
Biomedical and Environmental Sciences
Year:
2021
Document type:
Article