Advance in Role of IκB Kinase beta in Inflammatory Response Mechanism post Spinal Cord Injury (review) / 中国康复理论与实践
Chinese Journal of Rehabilitation Theory and Practice
; (12): 634-637, 2019.
Article
in Zh
| WPRIM
| ID: wpr-905606
Responsible library:
WPRO
ABSTRACT
IκB kinase beta (IKKbeta) is a key kinase in nuclear factor kappa B (NF-kappaB) signaling pathway. After spinal cord injury, IKKbeta is activated, and the signal pathway of NF-kappa B is abnormally activated, which produces a large number of inflammatory factors, which has a negative impact on the recovery of spinal cord injury. This article mainly summarized the structure and function of IKKbeta and its application in inflammatory reaction after spinal cord injury, trying to find a new target for the treatment of spinal cord injury.
Full text:
1
Database:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Rehabilitation Theory and Practice
Year:
2019
Document type:
Article