Prostate Carcinosarcoma Developing After Combined Pelvic External Beam Radiation Therapy and Androgen Deprivation Therapy
Korean Journal of Urological Oncology
; : 195-198, 2019.
Article
in En
| WPRIM
| ID: wpr-918248
Responsible library:
WPRO
ABSTRACT
Carcinosarcoma of the prostate is a very rare disease, which consists of carcinomatous and sarcomatous components. The prognosis of patients with prostatic carcinosarcoma is poor. An 80-year-old man who had been suffering from urinary retention and constipation with rectal pain visited a hospital. A patient with a history of combined pelvic external beam radiation therapy (EBRT) and androgen deprivation therapy (ADT) for prostate adenocarcinoma 7 years ago was diagnosed with secondary malignancy such as prostate carcinosarcoma by prostate biopsy. This is also a rare case occurring after combined EBRT and ADT for adenocarcinoma in a short interval. Then, he underwent chemotherapy for one cycle. Chemotherapy was stopped because of rapid clinical aggravation, and the patient died 5 months later. It is important to keep in mind the possibility of carcinosarcoma in the case that prostate-specific antigen maintains stable level but extent of tumor is gradually increased after EBRT or ADT.
Full text:
1
Database:
WPRIM
Type of study:
Prognostic_studies
Language:
En
Journal:
Korean Journal of Urological Oncology
Year:
2019
Document type:
Article