Research progress of respiratory syncytial virus (RSV) infection and respiratory diseases in infancy / 生理学报
Acta Physiologica Sinica
; (6): 1043-1053, 2021.
Article
in Zh
| WPRIM
| ID: wpr-921309
Responsible library:
WPRO
ABSTRACT
Lower respiratory tract infection (LRTI) induced by respiratory syncytial virus (RSV) is an important cause of hospitalization for infants. Compared with adults, infants are more likely to cause serious respiratory diseases after RSV infection due to the specific immature airway structure and immune system. The balance of immune resistance and immune tolerance of the host is critical to effective virus clearance and disease control. This paper reviews the relationship between RSV infection and respiratory diseases in infancy, the influence factors of the high pathogenicity of RSV infection in early life, as well as the research progress of anti-RSV therapy, and expands the specific molecular events regulating immune resistance and immune tolerance. We expect to present new ideas for the prevention and treatment of RSV-related respiratory diseases in clinical practice.
Full text:
1
Database:
WPRIM
Main subject:
Respiration Disorders
/
Respiratory Syncytial Viruses
/
Respiratory Tract Infections
/
Respiratory Syncytial Virus Infections
Limits:
Humans
/
Infant
Language:
Zh
Journal:
Acta Physiologica Sinica
Year:
2021
Document type:
Article