Non-alkaloid constituents of Hymenocallis littoralis / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 5304-5309, 2021.
Article
in Zh
| WPRIM
| ID: wpr-921676
Responsible library:
WPRO
ABSTRACT
Perennial herb Hymenocallis littoralis(Amaryllidaceae) boasts anti-tumor, anti-virus, and anti-inflammatory activities. As the representative constituents, alkaloids have attracted much attention, whereas the non-alkaloid constituents have been rarely reported. Therefore, this study investigated the non-alkaloid constituents of H. littoralis and their contribution to the various pharmacological activities of the herb. Thirteen non-alkaloid compounds were isolated from the 95% ethanol extract of dried whole plant of H. littoralis after a series of chromatographic separation steps and spectral analysis, and they were identified as 5,7-dihydroxy-6,8-dimethoxy-2-hydroxymethyl-4H-chromoen-4-one(1), undulatoside A(2),(2S)-7,4'-dihydroxyflavane(3), naringenin(4), 4',7-hydroxy-8-methylflavanone(5), 8-methylnaringenin(6), 8-demethylfarrerol(7), 6-methyl-aromadendrin(8), 4',5,7-trihydroxy-8-methylflavanone(9), syzalterin(10), 6-methylapigenin(11), isoliquiritigenin(12), and undatuside C(13) based on the spectroscopic data analysis. Among them, compound 1 was a new chromone derivative, and compounds 2 and 4-13 were isolated form this plant for the first time.
Key words
Full text:
1
Database:
WPRIM
Main subject:
Chromones
/
Liliaceae
/
Alkaloids
/
Amaryllidaceae
Language:
Zh
Journal:
China Journal of Chinese Materia Medica
Year:
2021
Document type:
Article