Application of intravenous immunoglobulin G in children with rheumatic diseases / 中华实用儿科临床杂志
Chinese Journal of Applied Clinical Pediatrics
; (24): 13-15, 2022.
Article
in Zh
| WPRIM
| ID: wpr-930360
Responsible library:
WPRO
ABSTRACT
The indications for the application of intravenous immunoglobulin G (IVIG) mainly include the replacement therapy of antibody deficiency diseases and immunomodulatory therapy with a high dose of IVIG.IVIG is extensively used in children with rheumatic diseases due to its immunomodulatory effects.However, most of them are " off-label drugs". In the treatment of pediatric rheumatic diseases, IVIG can benefit Kawasaki disease and primary immune thrombocytopenia, and may be beneficial in treating Sj?gren′s syndrome, dermatomyositis and systemic lupus erythematosus.However, for the patients with Stevens-Johnson syndrome, antineutrophil cyctoplasmic antibody (ANCA) asso-ciated vasculitis and systemic scleroderma, there is not much chance to obtain benefits.In the treatment of rheumatic diseases in children, the application of IVIG needs to be further standardized.
Full text:
1
Database:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Applied Clinical Pediatrics
Year:
2022
Document type:
Article