Research advances on thymosin β4 in promoting wound healing / 中华烧伤杂志
Chinese Journal of Burns
; (6): 378-384, 2022.
Article
in Zh
| WPRIM
| ID: wpr-936022
Responsible library:
WPRO
ABSTRACT
With the aging of population and the development of social economy, the incidence of chronic wounds is increasing day by day, while the incidence of burns and trauma remains at a high level, making wound repair an increasingly concerned area in clinical practice. Thymosin β4 is a naturally occurring small molecule protein in vivo, which is widely distributed in a variety of body fluids and cells, especially in platelets. Thymosin β4 has biological activities of promoting angiogenesis, anti-inflammation, anti-apoptosis, and anti-fibrosis, and has many important functions in wound repair. Thymosin β4 has been observed to promote the healing of various wounds, such as burns, diabetic ulcers, pressure ulcers. This paper will review the molecular structure, mechanism of wound healing promotion, pharmacokinetics, and clinical application of thymosin β4, aiming to introduce its potential in wound treatment and the shortcomings of current researches.
Full text:
1
Database:
WPRIM
Main subject:
Thymosin
/
Wound Healing
/
Burns
/
Pressure Ulcer
Limits:
Humans
Language:
Zh
Journal:
Chinese Journal of Burns
Year:
2022
Document type:
Article