Research progress in the theoretical connotation and mechanism of the eliminating dampness-heat method for the treatment of chronic kidney disease / 国际中医中药杂志
International Journal of Traditional Chinese Medicine
; (6): 113-116, 2023.
Article
in Zh
| WPRIM
| ID: wpr-989599
Responsible library:
WPRO
ABSTRACT
This article aimed to explore the theoretical connotation and mechanism of clearing damp-heat method in the treatment of chronic kidney disease (CKD), provide theoretical support for clearing damp-heat method in the treatment of chronic kidney disease, and further explain the modern scientific connotation of "damp-heat impairing kidney". Modern Traditional Chinese Medicine (TCM) believes that damp-heat is an important pathogenesis of kidney damage. Clearing damp-heat method plays a key role in inhibiting CKD immune inflammatory response, improving oxidative stress and antagonizing renal fibrosis. The mechanism is mainly related to the regulation of TNF-α level, blocking NF-κB signaling pathway, inhibiting inflammatory cytokines, antagonizing TGF-β1 secretion and other pathways.
Full text:
1
Database:
WPRIM
Language:
Zh
Journal:
International Journal of Traditional Chinese Medicine
Year:
2023
Document type:
Article