Pathological diagnosis and molecular alternations of pulmonary mucinous adenocarcinoma / 中国综合临床
Clinical Medicine of China
; (12): 246-250, 2023.
Article
in Chinese
| WPRIM (Western Pacific)
| ID: wpr-992498
Responsible library:
WPRO
ABSTRACT
Primary pulmonary mucinous adenocarcinoma is a rare subtype of lung adenocarcinoma. It differs from non-mucinous adenocarcinoma in etiology, pathogenesis, clinical, imaging, histological, immunophenotypic and genotypic features, prognosis and treatment. pulmonary mucinous adenocarcinoma mainly originates from bronchial basal cells and mucous cells. Tumor cells show a goblet and/or columnar cell morphology with abundant intracytoplasmic mucin and basally oriented nuclei, with a typical lepidic-predominant growth, the commonest molecular alterations are KRAS mutations.
Full text:
Available
Database:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Clinical Medicine of China
Year:
2023
Document type:
Article