Current researches of the role of dural immunity in neuroinfectious and neuroimmune diseases / 中华神经科杂志
Chinese Journal of Neurology
; (12): 572-577, 2023.
Article
in Zh
| WPRIM
| ID: wpr-994871
Responsible library:
WPRO
ABSTRACT
Dura mater, rich in vasculature and immune cells, is the outermost layer of the central nervous system, and thus acts as the first barrier to protect brain. Meningeal lymphatic vessels and immune cells are main components of dural immunity, which respond to a variety of central nervous system diseases. Meanwhile, compared with brain parenchyma, dura mater communicates more with peripheral tissues and is more susceptible to medical interventions. Therefore, dura mater is a promising target to prevent, diagnose and treat intracranial diseases. Here dural immunity is clarified based on meningeal lymphatic vessels and dural immune cells, and current researches inquiring the role of dural immunity in infectious and immune diseases of central nervous system are summarized.
Full text:
1
Database:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Neurology
Year:
2023
Document type:
Article