The importance of the postmortem interval for the diagnosis of WaterhouseFriderichsen syndrome by Neisseria meningitidis in a series of forensic cases
Autops. Case Rep
; 9(3): e2019103, July-Sept. 2019. ilus, tab
Artículo
en Inglés
| LILACS
| ID: biblio-1016864
Biblioteca responsable:
BR26.7
ABSTRACT
The effective value of microbiological post-mortem examinations stands as fundamental in forensic cases involving microbiology. We ran these analyses on five victims, who suddenly died after showing persistent fever. The examinations were conducted between 48 hours and 10 days after death, and adrenal gland apoplexy was detected in all the cases. Microbiological examinations identified Neisseria meningitidis, which was accountable for WaterhouseFriderichsen syndrome. Diplococci were isolated from three cadavers that underwent forensic dissection between 2 and 3 days after death. The remaining two cadavers showed polymicrobial contamination, and a polymerase chain reaction technique was necessary to identify the pathogen. We assumed that the microbial overlap could lead to diagnostic mistakes and conceal the identification of the lethal pathogen. Therefore, we suggest using molecular techniques for a postmortem interval (PMI) longer than 72 hours. Classical microbiological examination should be performed for PMI within 72 hours.
Texto completo:
Disponible
Colección:
Bases de datos internacionales
Base de datos:
LILACS
Asunto principal:
Autopsia
/
Síndrome de Waterhouse-Friderichsen
/
Técnicas Microbiológicas
Tipo de estudio:
Estudio diagnóstico
Límite:
Humanos
Idioma:
Inglés
Revista:
Autops. Case Rep
Asunto de la revista:
Anatomia
/
Patologia Cl¡nica
/
Patologia Legal
Año:
2019
Tipo del documento:
Artículo
País de afiliación:
Italia
Institución/País de afiliación:
Ospedale S. Carlo Borromeo/IT
/
Ospedale di Bergamo/IT
/
Università degli Studi di Bologna/IT
/
Università degli Studi di Milano/IT